Peculiarities of cellular, humoral links of immunity and dynamics of immunoglobulins in community-acquired pneumonia in adults and their importance for diagnostics and prognosis of the disease

The aim of our work was to study the characteristics immune status based on analysis cellular, humoral links immunity and dynamics immunoglobulins in adults with community-acquired pneumonia (CAP), their importance pathogenesis prognosis disease.
 Materials methods. carried out period 2017-2020 basis therapeutic department Municipal non-profit enterprise “City Clinical Multidisciplinary Hospital № 25” Kharkiv City Council. involved 20 adult patients CAP aged 18 80 years (mean age 36.5±10.3). control group consisted apparently healthy individuals 39.5±12.5). by determining phagocytic index, content lymphocytes, CD3+, CD4+, CD8+, CD16+, CD20+ level classes A, G, M disease: first tenth days after hospitalization.
 Results. On day hospitalization, there a significant imbalance phagocytosis, T- B-links immunity. treatment, number CD16+ increased. An increase Ig M, decrease A G were also noted. Thus, standard therapy for leads its clinical radiological resolution, but is not accompanied normalization parameters.
 Conclusions. features disorders revealed: increases cellular link immunity, CD3+ CD4+ decreases, no relative amount CD20+. There are changes status. For treatment CAP, addition pharmacotherapy, it necessary include drugs that stimulate system